Procalcitonin and Calcitonin Products

Procalcitonin (PCT) is a small protein that is synthesized by the C-cells in thyroid glands. In cells, PCT is further cleaved into three molecules: N-terminal fragment (N-terminal PCT), calcitonin and katacalcin.

PCT is considered to be the main marker of disorders that are accompanied by systemic inflammation and sepsis. In addition to sepsis and infection, the level of PCT can increase e.g. as a result of surgery, polytrauma, heat shock, burn injuries or cardiogenic shock. Monitoring PCT levels after cardiac surgery or heart transplantation helps to differentiate an acute graft rejection from bacterial or fungal infections.

For the development of PCT immunoassays we offer monoclonal antibodies that are specific to different fragments of the PCT molecule.

HyTest provides high quality PCT products to support your assay development

Antibodies

Cat.# Product name
4C10cc Calcitonin, in vitro, antibody
4C10   Calcitonin, human, antibody
4PC47 Procalcitonin, human, antibody
PPC3 Procalcitonin, polyclonal antibody

TechNotes

Procalcitonin (PCT) TechNotes.

In vitro –produced monoclonal mouse anti-human calcitonin

We now offer one of our anti-calcitonin mAbs also as an in vitro produced product (Cat.# 4C10cc).

Comparative titration of tag-free PCT from HyTest and from supplier A. Results show that there are no differences in immunoreactivities between the two proteins. Immunoreactivity was measured in sandwich ELISA using mAb pair 16B5-42.