Thrombin activatable fibrinolysis inhibitor (TAFI)

DATA SHEET

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Thrombin activatable fibrinolysis inhibitor (TAFI)
Cat.# 8TA1

Source:
Human plasma.
Plasma samples from donors were tested and found negative for HbsAg, HIV-1 and HIV-2
antibodies, HCV, and syphilis

Application:
Immunological and mass TAFI standard.
TAFI (synonyms: procarboxypeptidase B, carboxypeptidase U, carboxypeptidase R) is a plasma protein circulating as a zymogen. Being activated by thrombin-thrombomodulin complex during blood coagulation, it exerts carboxypeptidase activity. It splits out C-terminal lysine from fibrin and prevents fibrin lysis by plasmin. TAFI is considered as a risk factor for cardiovascular diseases.

Analysis:
Purity > 90 % (SDS-PAGE).
Protein concentration determined by the Lowry procedure.

Presentation:
Frozen in 10mM Tris-HCl buffer, pH 7.5, containing 0.15 M NaCl.

Storage:
– 20 °C.

References:
See all TAFI References