PAPP-A, heterotetrameric form (htPAPP-A)

 

DATA SHEET

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PAPP-A, heterotetrameric form (htPAPP-A)
Cat.# 8P64

Source:
Pooled human retroplacental blood.
Material was tested and found negative for HBsAg, HCV, HIV-1and 2 antibodies, HCV antibodies, and syphilis.

Composition:
Heterotetrameric complex, consisting of PAPP-A and pro-MBP subunits (PAPP-A/proMBP complex).

Applications:
Calibrator or standard for htPAPP-A or dPAPP-A assays. PAPP-A can be used for in vitro testing of Down syndrome and other fetal disorders.

Analysis:
Purity > 85 % (SDS-PAGE)

Immunological activity:
Immunological activity has been tested with monoclonal antibodies specific to PAPP-A.

Purification:
Ion-exchange chromatography, affinity chromatography, gel-filtration and negative immunoaffinity chromatography.

Presentation:
Lyophilized from solution in 10 mM Tris-HCl, 0.15 M NaCl, pH 7.5.
Product is recommended to reconstitute with distilled water.

Storage:
- 20 °C

Additional product information:
Pregnancy Associated Plasma Protein A (PAPP-A) TechNotes

References:
Search PAPP-A references from PubMed
See all PAPPA-A References

Related products:
Cat# 4P41: PAPP-A Human antibody
Cat# 4PD4: Human dimeric form of PAPP-A (dPAPP-A), antibody
Cat# 8P97: PAPP-A, homodimeric form (dPAPP-A), recombinant

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