TNF, Alpha, antibody
DATA SHEET
This data sheet is provided for information only.
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Monoclonal mouse anti- human alpha tumor necrosis factor
Cat.# 4T10
MAbs:
2C8, 1D9, F6C5, TA20, TA40, TA70
Hybridoma clones have been derived from hybridization of X63.Ag8.653 myeloma cells with spleen cells of Balb/c mice immunized with human recombinant tumor necrosis factor of aplha type.
Specificity:
MAb F6C5 is directed to different TNF-alpha epitope than MAbs 2C8 and 1D9. MAbs 2C8 and 1D9 are
effective in inhibition of the biological activity of recombinant and natural TNF-alpha.
MAbs TA20, TA40 and TA70 are specific to TNF-alpha.
MAb TA20 has neutralizing activity.
MAb isotypes:
IgG1 for MAbs 2C8, 1D9, F6C5, TA20, TA40, TA70
Applications:
MAbs 1D9 and 2C8 inhibit biological activity of TNF-alpha.
Recommended pair for sandwich immunoassay (coating-conjugate): 2C8 – F6C5.
MAbs 2C8, 1D9 and F6C5 work in immunohistochemistry.
MAb TA20 is working in Western blotting.
Purification:
Chromatography on protein A Sepharose for MAbs 2C8, 1D9, F6C5, TA20, TA40, TA70
Presentation:
PBS, pH 7.4, 0.1 % sodium azide (NaN3)
Storage:
+ 4 °C
Material safety note:
This product is sold as an antibody preparation for research use only. Standard Laboratory Practices should be followed when handling this material.
Contains sodium azide (0.1 %) as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
