Fatty Acid Binding Protein (FABP)
DATA SHEET
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Fatty acid binding protein (FABP), human
Cat.# 8F65
Source:
Human cardiac muscle tissue.
Blood sample from the tissue donor was tested and found negative for HBsAg, HIV-1 and HIV-2 antibodies, HCV, and syphilis.
FABP is a newly introduced plasma marker of acute myocardial infarction (AMI). The plasma kinetics of FABP (15 kD) closely resemble those of myoglobin in that elevated plasma concentrations are found within 2 hours after AMI and return to normal generally within 18 to 24 hours. But the concentration of FABP in the skeletal muscle is 20 times lower than in cardiac tissue (for myoglobin the same content for cardiac and skeletal tissue), that makes FABP to be more cardiac specific than
myoglobin. This makes FABP a useful biochemical marker for the early assessment or exclusion of AMI. FABP also appears to be a useful plasma marker for the estimation of myocardial infarct size.
Applications:
FABP is suitable for use as a standard in immunoassay for early detection of acute myocardial infarction, immunogen for antisera production, mass FABP standard, FABP biochemical and immunochemical studies, tracer for iodination.
Analysis:
Purity > 95 % (10 - 20 % gradient SDS-PAGE).
Immunological identity confirmed by reaction with monoclonal antibody that is specific for the fatty acid binding protein.
Presentation:
Lyophilized from protein solution in 10 mM Tris-HCl, pH 8.0.
Product is recommended to reconstitute with distilled water.
Storage:
- 20 °C
Additional product information:
Heart type fatty acid binding protein (H-FABP) TechNotes
References:
See all FABP References
Related products:
Cat# 4F29: Fatty Acid Binding Protein (FABP) antibody
Cat# 8FFS: FABP (Fatty Acid Binding Protein) free serum
See other Cardiac markers and blood coagulation products
